Treatment

Pharmacological treatment

Selective serotonin reuptake inhibitors (SSRIs) are the group of drugs classified according to the American Academy of Pediatrics (AAP) as "drugs whose effects are unknown and may be disturbing." However, data on their use during lactation are increasing rapidly. In addition, there are few reports of adverse effects on the baby. About long-term effect, there are not many studies. Let's meet some of the main SSRI, starting with Fluoxetine.

Fluoxetine is the drug with the highst number of usability studies during pregnancy and lactation. However, there is not enough data for a definitive conclusion about its safety.

  • The active metabolite of fluoxetine, the norfluoxetine, has a long half-life, which predisposes to serum accumulation in the children.

  • Some reported effects include: cramps, irritability, hyperactivity, tendency to leave the crying child and reduced weight gain.

  • These effects are resolved with discontinuation of exposure to fluoxetine. Other studies show that the weight at the end of 6 months was not different from the average.